Immunology

Antigen presentation in the form of an immunological synapse between dendritic cell and t cell, love is in the air

Immunological Synapse

Antigen presentation in the form of an immunological synapse between dendritic cell and t cell, love is in the air

In an immunological synapse the membrane between the antigen presenting cell (APC) and the t cell touch. They exchange signals so the APC can present an antigen to the t cell. In this case the APC is a dendritic cell that has the right antigen for the t cell and love is in the air. …

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Plasma cell; B cell; shooting antibodies with a sling

Shooting Antibodies

Plasma cell; B cell; shooting antibodies with a sling

Plasma cells, are a specialized type of B cells that produce large volumes of antibodies. This B cell here is using those antibodies to neutralize an invading flu virus that has entered the body.

neutrophil phagocytosis of bacteria

Phagocytosis

Phagocytosis is the process by which particulate material is endocytosed (“eaten”) by a cell (From Greek phagein, to eat.). The process of phagocytosis is one of the many different ways our immune cells fight infections. Macrophages and neutrophils are cells of the immune system that use phagocytosis to bind and ingest invading microorganisms. Phagocytosis is …

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Adoptive cell transfer of CD45.2 T lymphocytes to new host CD45.1 mouse host

Adoptive Cell Transfer

Adoptive cell transfer of CD45.2 T lymphocytes to new host CD45.1 mouse host

Adoptive cell transfer refers to the transfer of cells into an organism, which could be a patient or in the case of this cartoon, a mouse. This is a very common technique used in immunology research to understand how the cells behave. Adoptive Cell Transfer in Immunology Research Typically, the cells that are being transfer …

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Cartoon Host-Pathogen Arm Wrestling

Host-Pathogen Battles

Cartoon Host-Pathogen Arm Wrestling

This cartoon is showing the battle between a leukocyte and a bacterium. Who will win? The interactions between the host cell and a pathogen trying to invade an organism, commonly referred to as host-pathogen interactions, are very important to understand disease. Each pathogen might have a unique way of interacting with their host and the …

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cartoon of monocyte-dericed dendritic cell

Monocyte-Derived Dendritic Cell

cartoon of monocyte-dericed dendritic cell

This monocyte turned into a dendritic cell (DC) and doesn’t even know how it happened! Many researchers isolate monocytes and then derive them into DCs to do studies on these cells. It is a common method followed by people studying DCs that need to generate some cells for their experiments. In case you are interested in …

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Cartoon of Dendritic Cell Presenting Antigen on MHC to T Cell

MHC Restriction

Cartoon of Dendritic Cell Presenting Antigen on MHC to T Cell

The dendritic cell (DC) is presenting an antigen to a T cell but the T cell doesn’t recognize it. This is making the DC kind of sad. In this case the DC is presenting the antigen on an MHC-I molecule and it is showing to a CD8 T cells. However, the T cell will recognize and …

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Cartoon of granulocytes: neutrophil, basophil and eosinophil

The Gran Team

Cartoon of granulocytes: neutrophil, basophil and eosinophil

These feisty granulocytes will defeat any bacteria, fungus or parasite that wants to mess with them. Check out the full blog post on granulocytes to lear more about each one of these cells.

Cartoon of granulocytes: neutrophil, basophil and eosinophil

Granulocytes

The granulocytes are so called because they have densely granules in their cytoplasm; they are also called polymorphonuclear leukocytes because of their lobulated nuclei. There are three types of granulocytes: Neutrophils can perform phagocytosis and are the most abundant type of granulocytes and the most abundant type of white blood cells overall in most mammals. Eosinophils make up …

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